Anecdotal evidence indicates that individuals diagnosed with ASD often have an affinity for various technologies such as laptop computers and iPads. However, there are few instances of studies rigorously demonstrating the clinical utility of such technologies. The aim of the panel is to explore the clinical usefulness of various technologies and how they may or may not be able to provide clinical benefits to individuals diagnosed with ASD. We will address the current research literature surrounding such technologies looking at both their ability to provide clinical benefit for treating those with ASD as well as the limitations of the current research literature (e.g., generalization of learning). In addition, we will discuss the challenges faced when deploying such technologies in ‘real-world’ clinical setting (e.g, variance in physical settings, variance in cognitive functioning) and the implications for future designs. Finally, we will explore how ‘new-to-the-world’ technologies (e.g, Microsoft Kinect, Google Glass) may be able to provide an even greater opportunity for more effective treatments for individuals diagnosed with ASD.