Gender and sexual minorities (GSM) are estimated to comprise between 4% and 10% of the population, but are twice as likely to experience mental health problems. Social stigma and a lack of laws to protect their rights are some of the major contributors of increased stress, anxiety, depression, substance abuse, and suicidal ideation for the LGBTQIA+ population. GSM can also be reluctant to seek treatment, as there is a mistrust of healthcare providers that has built up due to a history of discrimination, a lack of training, and shortage of understanding of the experiences of GSM. Behavior analytic and behaviorally-inspired interventions are amongst the most effective for treating depression, substance abuse, anxiety, and other psychological difficulties. Behavior analysis has only recently, however, begun to make a unique contribution to conceptualizing and addressing LGBTQIA+ issues. The purpose of this panel is to offer perspectives on the status of behavior analytic contributions to promoting GSM well-being, in terms of building a robust body of behavior analytic research and developing and making available behavior analytic services. Discussants will also address the contingencies that have slowed the progress of behavior analysis in this domain as well as ethical matters involving GSM.